Korean J healthc assoc Infect Control Prev 2018; 23(2): 80-85
Published online December 31, 2018 https://doi.org/10.14192/kjhaicp.2018.23.2.80
Copyright © Korean Society for Healthcare-associated infection Control and Prevention
Noori Lee1, Sanghee Park1, Jiyeon Kim1, Keyyoung Kim2, Daeyeon Kim3
Clinical Research Center, Masan National Tuberculosis Hospital1, Changwon, Institute of Environmental and Industrial Medicine, Hanyang University2, Seoul, Masan National Tuberculosis Hospital3, Changwon, Korea
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background: Tuberculosis is an infectious disease, -spreading from person to person through the air. When a person with infectious tuberculosis coughs or sneezes, tiny particles containing Mycobacterium tuberculosis are expelled into the air and remain suspended for several hours. Therefore, it is important to control the transmission of M. tuberculosis through air. This study was conducted to determine the inactivation efficacy of the plasma generator against the M. tuberculosis.Methods: The attenuated M. tuberculosis H37Ra inoculated on the solid medium were placed in hospital wards and BL3 laboratory, with a plasma generator (Model TB-500, Shinyoung Airtech, Seongnam-si, Korea) being operated at specific time intervals. The growth of M. tuberculosis was determined by plasma exposure time.Results: M. tuberculosis samples exposed to non-thermal plasma for 3, 6, 9, and 24 h showed inhibition effects of 45-75%, 69-86%, 93-100%, and 100%, respectively. Thus, it was found that the inhibition effect of plasma generators against M. tuberculosis were proportional to the plasma exposure time. Conclusion: The non-thermal atmospheric pressure plasma generator technique may be applied as a promising technique for the prevention of M. tuberculosis infection in healthcare and other public facilities, when operated for more than 9 h.
Keywords: Inactivation, Mycobacterium tuberculosis, Plasma, Tuberculosis
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