Korean J healthc assoc Infect Control Prev 2009; 14(2): 98-102
Published online December 31, 2009 https://doi.org/10.14192/kjicp.2009.14.2.98
Copyright © Korean Society for Healthcare-associated infection Control and Prevention
Hye Ran Jeong1, Bong Hee Kim1, Hyo Youl Kim2, Young Keun Kim2, Young Uh3, and Hei Kyung Jin3
Infection Control Office1, Division of Infectious Diseases2, and Department of Laboratory Medicine3, Wonju Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background: Recently, the incidence of hepatitis A virus (HAV) infection has been increasing in Korea, and an outbreak among healthcare workers (HCWs) has also been reported. This study aims to evaluate the seroepidemiology of hepatitis A among HCWs at an 820-bed teaching hospital in Korea, thereby facilitating HAV vaccination for these HCWs.
Methods: In June 2009, we assessed the total immunoglobulins against the HAV in the serum samples of 907 HCWs by using VIDAS Anti-HAV Total (bioMérieux, France).
Results: Seropositivity for HAV significantly increased with age (P＜0.001): 0% for ≤25 years, 9.4% for 26-30 years, 39.5% for 31-35 years, 66.7% for 36-40 years, 85.7% for 41-45 years, 96.0% for 46-50 years, 98.3% for 51-55 years, 95.8% for 56-60 years, and 100% for ≥61 years.
Conclusion: Since HCWs aged 20-40 years show low seropositivity for HAV vaccination against hepatitis A should be considered in all these HCWs.
Keywords: Hepatitis A virus, Healthcare workers, Seroprevalence, Vaccination, Hepatitis A antibodies
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