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Korean J healthc assoc Infect Control Prev 2024; 29(2): 93-102

Published online December 31, 2024 https://doi.org/10.14192/kjicp.2024.29.2.93

Copyright © Korean Society for Healthcare-associated infection Control and Prevention

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Implant-associated Infections: Role of Biofilms, Diagnosis and Prevention

Yu Mi Wi

Samsung Changwon Hospital, Sungkyunkwan University, Changwon, Korea

Correspondence to: Yu Mi Wi
E-mail: yumi.wi@samsung.com
ORCID: https://orcid.org/0000-0003-3625-3328

Received: November 3, 2024; Revised: November 16, 2024; Accepted: January 18, 2024

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0).

Abstract

Implant-associated infections pose significant challenges for diagnosis and treatment due to the formation of biofilm on device surfaces. Biofilms are complex microbial communities that adhere to surfaces and are encased in a self-produced extracellular polymeric substance (EPS) matrix. Their presence on implants can lead to persistent infections, implant failure, and increased morbidity and mortality. This review explores the role of biofilms in the pathogenesis of implant-associated infections and examines current strategies for their diagnosis and prevention.

Keywords: Implant, Biofilms, Extracellular polymeric substance, Infection, Prevention

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