대한의료관련감염관리학회 Korean Society for Healthcare-associated infection Control and Prevention.

pISSN 0705-3797. eISSN 2586-1298.

Comparison of characteristics of patients admitted to the homeless ward based on CRE colonization

CRE n=18 non-CRE n=106 Total n=124 Univariate analysis Multivariate analysis
OR (95% CI) P aOR (95% CI) P
Age, median (IQR) 69.5 (65.0-75.0) 62.0 (55.0-69.0) 64.0 (55.0-70.0) 1.061 (1.008-1.117) 0.024 1.071 (1.014-1.132) 0.014
Sex, male (%)a 18 (100.0%) 103 (97.2%) 121 (97.6%)
CRE colonization previous three months, n (%)a 3 (16.7%) 0 (0.0%) 3 (2.4%)
Antibiotics exposure previous three months, n (%) 4 (22.2%) 4 (3.8%) 8 (6.5%) 7.286 (1.635-32.465) 0.009 6.796 (1.215-38.029) 0.029
Hospitalization previous year, n (%) 8 (44.4%) 29 (27.4%) 37 (29.8%) 2.124 (0.764-5.909) 0.149
Underlying diseases, n (%)
Hypertension 9 (50.0%) 40 (37.7%) 49 (39.5%) 1.643 (0.529-5.112) 0.435
Diabetes mellitus 7 (38.9%) 28 (26.4%) 35 (28.2%) 1.773 (0.601-4.965) 0.421
Malignancy 8 (44.4%) 21 (19.8%) 29 (23.4%) 3.238 (1.115-9.248) 0.048
Heart 1 (5.6%) 19 (17.9%) 20 (16.1%) 0.269 (0.015-1.442) 0.331
Kidney 5 (27.8%) 8 (7.5%) 13 (10.5%) 4.712 (1.267-16.458) 0.030
Liver 4 (22.2%) 20 (18.9%) 24 (19.4%) 1.229 (0.322-3.864) 0.992
Pulmonary 5 (27.8%) 21 (19.8%) 26 (21.0%) 1.557 (0.459-4.651) 0.649
Neurological 6 (33.3%) 20 (18.9%) 26 (21.0%) 2.150 (0.680-6.276) 0.280
Outcomes, n (%)
Other MDR colonizationb 10 (55.6%) 15 (14.2%) 25 (20.2%) 7.583 (2.604-23.031) <0.001 7.168 (2.224-23.096) 0.001
Hospital days, median (IQR) 28.5 (22.0-55.0) 9.0 (5.0-19.0) 10.5 (6.0-24.5) 7.168 (2.224-23.096) 0.007
In-hospital mortality 3 (16.7%) 6 (5.7%) 9 (7.3%) 3.333 (0.651-14.139) 0.241

aStatistical comparison was not possible due to the small number of cases.

bMDR bacterial colonization was assessed by reviewing culture results of all clinical samples during hospitalization. Colonization with methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococcus, carbapenem-resistant Acinetobacter baumannii, or carbapenem-resistant Pseudomonas aeruginosa was considered colonization of MDR bacteria if any one of these was detected.

Abbreviations: CRE, carbapenem-resistant Enterobacterales; OR, odds ratio; aOR, adjusted odds ratio; CI, confidence interval; SD, standard deviation; MDR, multidrug-resistant; IQR, interquartile range.

Korean J healthc assoc Infect Control Prev 2024;29:128~136 https://doi.org/10.14192/kjicp.2024.29.2.128
© Korean J healthc assoc Infect Control Prev