Comparison of H5N1 and H7N9 avian influenza cases in human [24,34]
H5N1 | H7N9 | |
---|---|---|
Key factor of spread | Wild bird migration, poultry trade route | Live bird market |
Median age | 18-26 years | 62 years |
Case fatality rate | 50%-60% | 30%-40% |
Male (%) | 51% | 71% |
Incubation period | 4 (2-8) | 6 (1-10) |
Estimated R0 | 0.06-1.14 | 0.10-0.47 |
Exposure to poultry | 58%-84% | 56%-75% |
Human tropism mutation | N/A | T160A, Q226L, E627K |
Exposure level | High-level (slaughtering of sick/dead birds) | Low-level (walk through LBM) |
Median time from admission to death | 5.7 days | 12.0 days |
Fever ≥38℃ | 65% | 79% |
Cough | 54% | 71% |
Sore throat | 5% | 9% |
Shortness of breath | 8% | 13% |