Characteristics of patients and result of intervention for long-term prescription of carbapenem
Age [median (IQR)] | 68 (60-73.25) |
Sex [Male, (%)] | 30 (71.4) |
Duration of carbapenem use before intervention [days, median (IQR)] | 19 (18.0-26.5) |
Admission to the ICU during the period of carbapenem administration [N, (%)] | 17 (40.5) |
Site of infection [N, (%)] | |
Pneumonia | 23 (54.8) |
Intra-abdominal infection | 7 (16.7) |
Bacteremia | 4 (9.5) |
Hepatobiliary infection | 3 (7.1) |
Neutropenic fever | 2 (4.8) |
Deep neck infection, Surgical site infection, Urinary tract infection | |
Recommendation for termination of carbapenem through medical records before intervention [N, (%)] | 30 (71.4) |
Duration from intervention to discontinuation of carbapenem [days, median (IQR)] | 1 (0-3.75) |
Compliance of intervention [N, (%)] | 40 (95.2) |
Result of intervention [N, (%)] | |
1) Discontinuation of antibiotics | 19 (47.5) |
2) Change of narrow-spectrum antibiotics | 21 (52.5) |
Piperacillin/tazobactam | 14 (66.6) |
Cefepime | 2 (9.5) |
Ceftriaxone | 2 (9.5) |
Duration of changed antibiotics usage [days, median (IQR)] | 16 (7-26) |
Recurred infection within 30 days after discontinuation of carbapenem [N, (%)] | 2 (4.8) |
Mortality within 30 days after discontinuation of carbapenem [N, (%)] | 8 (19.0) |