대한의료관련감염관리학회 Korean Society for Healthcare-associated infection Control and Prevention.

pISSN 0705-3797. eISSN 2586-1298.

Testing modalities of Clostridioides difficile infection

Test Sensitiviy [18] Specificity [18] Distinguishes colonization from active infection [18] Substance detected [6]
Toxigenic culture 94% 99% No C. difficile vegetative cells or spores
Cell cytotoxicity neutralization assay 93% 98% Yes Free toxins
Glutamate dehydrogenase test 94-96% 90-96% No C. difficile common antigen
Nucleic acid amplification tests 95-96% 94-98% No C. difficile toxin gene
Toxin A and B enzyme immunoassay 57-83% 99% Yes Free toxins

This table was based and modified from Guideline of Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) and guideline of American College of Gastroenterology (ACG) [6,18].

Korean J healthc assoc Infect Control Prev 2021;26:70~82 https://doi.org/10.14192/kjicp.2021.26.2.70
© Korean J healthc assoc Infect Control Prev